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BMCBI
2005
124views more  BMCBI 2005»
13 years 7 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2004
207views more  BMCBI 2004»
13 years 7 months ago
Computational identification of transcription factor binding sites by functional analysis of sets of genes sharing overrep-resen
Background: Transcriptional regulation is a key mechanism in the functioning of the cell, and is mostly effected through transcription factors binding to specific recognition moti...
Davide Corà, Ferdinando Di Cunto, Paolo Pro...
BMCBI
2007
103views more  BMCBI 2007»
13 years 7 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang
KDD
2005
ACM
137views Data Mining» more  KDD 2005»
14 years 8 months ago
Pattern-based similarity search for microarray data
One fundamental task in near-neighbor search as well as other similarity matching efforts is to find a distance function that can efficiently quantify the similarity between two o...
Haixun Wang, Jian Pei, Philip S. Yu
SEMWEB
2009
Springer
14 years 2 months ago
Developing an Ontology from the Application Up
 The  biomedical  ontology  community  is  producing  ontologies  which   represent   biological   knowledge   and   with   a   bias   towards   a   realist   pe...
James Malone, Tomasz Adamusiak, Ele Holloway, Mish...