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» Ensemble Based Data Fusion for Gene Function Prediction
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BMCBI
2007
147views more  BMCBI 2007»
13 years 10 months ago
Predicting combinatorial binding of transcription factors to regulatory elements in the human genome by association rule mining
Background: Cis-acting transcriptional regulatory elements in mammalian genomes typically contain specific combinations of binding sites for various transcription factors. Althoug...
Xochitl C. Morgan, Shulin Ni, Daniel P. Miranker, ...
BMCBI
2010
113views more  BMCBI 2010»
13 years 10 months ago
Improving performance of mammalian microRNA target prediction
Background: MicroRNAs (miRNAs) are single-stranded non-coding RNAs known to regulate a wide range of cellular processes by silencing the gene expression at the protein and/or mRNA...
Hui Liu, Dong Yue, Yidong Chen, Shou-Jiang Gao, Yu...
MAGS
2007
100views more  MAGS 2007»
13 years 10 months ago
Engineering agent-mediated integration of bioinformatics analysis tools
Abstract. The availability of massive amounts of biological data, distributed in various data sources, has prompted the development of a wide range of data analysis tools. However,...
Vassilis Koutkias, Andigoni Malousi, Nicos Maglave...
NAR
2006
85views more  NAR 2006»
13 years 10 months ago
WormBase: better software, richer content
WormBase (http://wormbase.org), the public database for genomics and biology of Caenorhabditis elegans, has been restructured for stronger performance and expanded for richer biol...
Erich M. Schwarz, Igor Antoshechkin, Carol Bastian...
NAR
2008
107views more  NAR 2008»
13 years 10 months ago
MutDB: update on development of tools for the biochemical analysis of genetic variation
Understanding how genetic variation affects the molecular function of gene products is an emergent area of bioinformatic research. Here, we present updates to MutDB (http://www.mu...
Arti Singh, Adebayo Olowoyeye, Peter H. Baenziger,...