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BMCBI
2006
211views more  BMCBI 2006»
13 years 6 months ago
Missing value estimation for DNA microarray gene expression data by Support Vector Regression imputation and orthogonal coding s
Background: Gene expression profiling has become a useful biological resource in recent years, and it plays an important role in a broad range of areas in biology. The raw gene ex...
Xian Wang, Ao Li, Zhaohui Jiang, Huanqing Feng
BMCBI
2007
166views more  BMCBI 2007»
13 years 6 months ago
Data handling strategies for high throughput pyrosequencers
Background: New high throughput pyrosequencers such as the 454 Life Sciences GS 20 are capable of massively parallelizing DNA sequencing providing an unprecedented rate of output ...
Gabriele A. Trombetti, Raoul J. P. Bonnal, Ermanno...
BMCBI
2004
114views more  BMCBI 2004»
13 years 6 months ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....
BMCBI
2008
181views more  BMCBI 2008»
13 years 5 months ago
Assessing batch effects of genotype calling algorithm BRLMM for the Affymetrix GeneChip Human Mapping 500 K array set using 270
Background: Genome-wide association studies (GWAS) aim to identify genetic variants (usually single nucleotide polymorphisms [SNPs]) across the entire human genome that are associ...
Huixiao Hong, Zhenqiang Su, Weigong Ge, Leming M. ...
BMCBI
2006
184views more  BMCBI 2006»
13 years 6 months ago
PubFocus: semantic MEDLINE/PubMed citations analytics through integration of controlled biomedical dictionaries and ranking algo
Background: Understanding research activity within any given biomedical field is important. Search outputs generated by MEDLINE/PubMed are not well classified and require lengthy ...
Maksim V. Plikus, Zina Zhang, Cheng-Ming Chuong