Background: Normalization is the process of removing non-biological sources of variation between array experiments. Recent investigations of data in gene expression databases for ...
Timothy Lu, Christine M. Costello, Peter J. P. Cro...
Abstract. One of the key applications of microarray studies is to select and classify gene expression profiles of cancer and normal subjects. In this study, two hybrid approaches
Background: Gene expression profiling has become a useful biological resource in recent years, and it plays an important role in a broad range of areas in biology. The raw gene ex...
Background: Chromatin immunoprecipitation on tiling arrays (ChIP-chip) has been widely used to investigate the DNA binding sites for a variety of proteins on a genome-wide scale. ...
Shouyong Peng, Artyom A. Alekseyenko, Erica Larsch...
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...