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» Evolution of Biological Complexity
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BMCBI
2007
78views more  BMCBI 2007»
13 years 10 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
BMCBI
2007
247views more  BMCBI 2007»
13 years 10 months ago
A survey of DNA motif finding algorithms
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Modan K. Das, Ho-Kwok Dai
BMCBI
2007
172views more  BMCBI 2007»
13 years 10 months ago
Bayesian approaches to reverse engineer cellular systems: a simulation study on nonlinear Gaussian networks
Background: Reverse engineering cellular networks is currently one of the most challenging problems in systems biology. Dynamic Bayesian networks (DBNs) seem to be particularly su...
Fulvia Ferrazzi, Paola Sebastiani, Marco Ramoni, R...
JCB
2006
107views more  JCB 2006»
13 years 10 months ago
Protein Image Alignment via Piecewise Affine Transformations
Abstract We present a new approach for aligning families of 2D gels. Instead of choosing one of the gels as reference and performing pairwise alignment, we construct an ideal gel t...
Florian A. Potra, Xing Liu, Françoise Seill...
IIE
2007
114views more  IIE 2007»
13 years 9 months ago
Design and Implementation of a Logo-based Computer Graphics Course
Two years ago the Faculty of Mathematics and Informatics at Sofia University makes a decision to design a new series of Logo-based courses which make use of the modern technology....
Pavel Boytchev