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» Evolution of Biological Complexity
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BMCBI
2005
201views more  BMCBI 2005»
13 years 8 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
BMCBI
2005
169views more  BMCBI 2005»
13 years 8 months ago
Genetic interaction motif finding by expectation maximization - a novel statistical model for inferring gene modules from synthe
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Yan Qi 0003, Ping Ye, Joel S. Bader
BMCBI
2005
157views more  BMCBI 2005»
13 years 8 months ago
Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome bro
Background: To facilitate efficient selection and the prioritization of candidate complex disease susceptibility genes for association analysis, increasingly comprehensive annotat...
Judith E. Stenger, Hong Xu, Carol Haynes, Elizabet...
CAD
2005
Springer
13 years 8 months ago
Bayesian computer-aided experimental design of heterogeneous scaffolds for tissue engineering
This paper presents a Bayesian methodology for computer-aided experimental design of heterogeneous scaffolds for tissue engineering applications. These heterogeneous scaffolds hav...
Lee E. Weiss, Cristina H. Amon, Susan Finger, Eric...
CANDC
2005
ACM
13 years 8 months ago
Comments on selected fundamental aspects of microarray analysis
Microarrays are becoming a ubiquitous tool of research in life sciences. However, the working principles of microarray-based methodologies are often misunderstood or apparently ig...
Alessandra Riva, Anne-Sophie Carpentier, Bruno Tor...