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BMCBI
2010
136views more  BMCBI 2010»
13 years 7 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
ICCAD
2009
IEEE
147views Hardware» more  ICCAD 2009»
13 years 5 months ago
SAT-based protein design
Computational protein design can be formulated as an optimization problem, where the objective is to identify the sequence of amino acids that minimizes the energy of a given prot...
Noah Ollikainen, Ellen Sentovich, Carlos Coelho, A...
BMCBI
2006
202views more  BMCBI 2006»
13 years 7 months ago
DWARF - a data warehouse system for analyzing protein families
Background: The emerging field of integrative bioinformatics provides the tools to organize and systematically analyze vast amounts of highly diverse biological data and thus allo...
Markus Fischer, Quan K. Thai, Melanie Grieb, J&uum...
ALIFE
1998
13 years 7 months ago
Evolutionary Body Building: Adaptive Physical Designs for Robots
Creating artificial life forms through evolutionary robotics faces a “chicken and egg” problem: learning to control a complex body is dominated by problems specific to its s...
Pablo Funes, Jordan B. Pollack
BMCBI
2005
123views more  BMCBI 2005»
13 years 7 months ago
PSI-BLAST-ISS: an intermediate sequence search tool for estimation of the position-specific alignment reliability
Background: Protein sequence alignments have become indispensable for virtually any evolutionary, structural or functional study involving proteins. Modern sequence search and com...
Mindaugas Margelevicius, Ceslovas Venclovas