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BMCBI
2004
131views more  BMCBI 2004»
13 years 9 months ago
Alternative mapping of probes to genes for Affymetrix chips
Background: Short oligonucleotide arrays have several probes measuring the expression level of each target transcript. Therefore the selection of probes is a key component for the...
Laurent Gautier, Morten Møller, Lennart Fri...
BMCBI
2002
134views more  BMCBI 2002»
13 years 9 months ago
CoreGenes: A computational tool for identifying and cataloging "core" genes in a set of small genomes
Background: Improvements in DNA sequencing technology and methodology have led to the rapid expansion of databases comprising DNA sequence, gene and genome data. Lower operational...
Nikhat Zafar, Raja Mazumder, Donald Seto
BMCBI
2011
13 years 4 months ago
Worm Phenotype Ontology: integrating phenotype data within and beyond the C. elegans community
Background: Caenorhabditis elegans gene-based phenotype information dates back to the 1970’s, beginning with Sydney Brenner and the characterization of behavioral and morphologi...
Gary Schindelman, Jolene Fernandes, Carol Bastiani...
BMCBI
2011
13 years 1 months ago
Estimation of allele frequency and association mapping using next-generation sequencing data
Background: Estimation of allele frequency is of fundamental importance in population genetic analyses and in association mapping. In most studies using next-generation sequencing...
Su Yeon Kim, Kirk E. Lohmueller, Anders Albrechtse...
BMCBI
2007
133views more  BMCBI 2007»
13 years 10 months ago
GenMAPP 2: new features and resources for pathway analysis
Background: Microarray technologies have evolved rapidly, enabling biologists to quantify genome-wide levels of gene expression, alternative splicing, and sequence variations for ...
Nathan Salomonis, Kristina Hanspers, Alexander C. ...