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» Evolving fuzzy rules to model gene expression
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BCB
2010
127views Bioinformatics» more  BCB 2010»
13 years 2 months ago
A novel network model for molecular prognosis
Network-based genome-wide association studies (NWAS) utilize the molecular interactions between genes and functional pathways in biomarker identification. This study presents a no...
Ying-Wooi Wan, Swetha Bose, James Denvir, Nancy La...
BIOSYSTEMS
2007
175views more  BIOSYSTEMS 2007»
13 years 8 months ago
Alternative routes and mutational robustness in complex regulatory networks
Alternative pathways through a gene regulation network connect a regulatory molecule to its (indirect) regulatory target via different intermediate regulators. We here show for tw...
Andreas Wagner, Jeremiah Wright
BMCBI
2005
141views more  BMCBI 2005»
13 years 7 months ago
Construction and validation of the APOCHIP, a spotted oligo-microarray for the study of beta-cell apoptosis
Background: Type 1 diabetes mellitus (T1DM) is a autoimmune disease caused by a long-term negative balance between immune-mediated beta-cell damage and beta-cell repair/regenerati...
Nils E. Magnusson, Alessandra K. Cardozo, Mogens K...
GECCO
1999
Springer
130views Optimization» more  GECCO 1999»
14 years 2 days ago
Heterochrony and Adaptation in Developing Neural Networks
This paper discusses the simulation results of a model of biological development for neural networks based on a regulatory genome. The model’s results are analyzed using the fra...
Angelo Cangelosi
BMCBI
2007
111views more  BMCBI 2007»
13 years 7 months ago
CATMA, a comprehensive genome-scale resource for silencing and transcript profiling of Arabidopsis genes
Background: The Complete Arabidopsis Transcript MicroArray (CATMA) initiative combines the efforts of laboratories in eight European countries [1] to deliver gene-specific sequenc...
Gert Sclep, Joke Allemeersch, Robin Liechti, Bj&ou...