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SAC
2006
ACM
14 years 1 months ago
Mining and analyzing the topological structure of protein-protein interaction networks
We report a comprehensive evaluation of the topological structure of protein-protein interaction (PPI) networks by mining and analyzing graphs constructed from the publicly availa...
Daniel Duanqing Wu, Xiaohua Hu
GECCO
2010
Springer
191views Optimization» more  GECCO 2010»
14 years 13 days ago
Initialization parameter sweep in ATHENA: optimizing neural networks for detecting gene-gene interactions in the presence of sma
Recent advances in genotyping technology have led to the generation of an enormous quantity of genetic data. Traditional methods of statistical analysis have proved insufficient i...
Emily Rose Holzinger, Carrie C. Buchanan, Scott M....
KDD
2012
ACM
201views Data Mining» more  KDD 2012»
11 years 10 months ago
Learning from crowds in the presence of schools of thought
Crowdsourcing has recently become popular among machine learning researchers and social scientists as an effective way to collect large-scale experimental data from distributed w...
Yuandong Tian, Jun Zhu
BIOINFORMATICS
2011
12 years 11 months ago
A method for probing the mutational landscape of amyloid structure
Motivation: Proteins of all kinds can self-assemble into highly ordered β-sheet aggregates known as amyloid fibrils, important both biologically and clinically. However, the spe...
Charles W. O'Donnell, Jérôme Waldisp&...
RECOMB
2007
Springer
14 years 1 months ago
Network Legos: Building Blocks of Cellular Wiring Diagrams
Publicly-available data sets provide detailed and large-scale information on multiple types of molecular interaction networks in a number of model organisms. These multi-modal univ...
T. M. Murali, Corban G. Rivera