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BMCBI
2007
129views more  BMCBI 2007»
13 years 10 months ago
A novel approach to sequence validating protein expression clones with automated decision making
Background: Whereas the molecular assembly of protein expression clones is readily automated and routinely accomplished in high throughput, sequence verification of these clones i...
Elena Taycher, Andreas Rolfs, Yanhui Hu, Dongmei Z...
BMCBI
2007
143views more  BMCBI 2007»
13 years 10 months ago
Factor analysis for gene regulatory networks and transcription factor activity profiles
Background: Most existing algorithms for the inference of the structure of gene regulatory networks from gene expression data assume that the activity levels of transcription fact...
Iosifina Pournara, Lorenz Wernisch
BMCBI
2007
108views more  BMCBI 2007»
13 years 10 months ago
Computer-aided identification of polymorphism sets diagnostic for groups of bacterial and viral genetic variants
Background: Single nucleotide polymorphisms (SNPs) and genes that exhibit presence/absence variation have provided informative marker sets for bacterial and viral genotyping. Iden...
Erin P. Price, John Inman-Bamber, Venugopal Thiruv...
BMCBI
2008
160views more  BMCBI 2008»
13 years 10 months ago
VariVis: a visualisation toolkit for variation databases
Background: With the completion of the Human Genome Project and recent advancements in mutation detection technologies, the volume of data available on genetic variations has rise...
Timothy D. Smith, Richard G. H. Cotton
BMCBI
2007
164views more  BMCBI 2007»
13 years 10 months ago
The Personal Sequence Database: a suite of tools to create and maintain web-accessible sequence databases
Background: Large molecular sequence databases are fundamental resources for modern bioscientists. Whether for project-specific purposes or sharing data with colleagues, it is oft...
Scott A. Givan, Christopher M. Sullivan, James C. ...
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