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TMI
2002
248views more  TMI 2002»
13 years 7 months ago
Adaptive Elastic Segmentation of Brain MRI via Shape Model Guided Evolutionary Programming
This paper presents a fully automated segmentation method for medical images. The goal is to localize and parameterize a variety of types of structure in these images for subsequen...
Alain Pitiot, Arthur W. Toga, Paul M. Thompson
BMCBI
2006
85views more  BMCBI 2006»
13 years 7 months ago
Identification of physicochemical selective pressure on protein encoding nucleotide sequences
Background: Statistical methods for identifying positively selected sites in protein coding regions are one of the most commonly used tools in evolutionary bioinformatics. However...
Wendy S. W. Wong, Raazesh Sainudiin, Rasmus Nielse...
RECOMB
2003
Springer
14 years 8 months ago
Modeling dependencies in protein-DNA binding sites
The availability of whole genome sequences and high-throughput genomic assays opens the door for in silico analysis of transcription regulation. This includes methods for discover...
Yoseph Barash, Gal Elidan, Nir Friedman, Tommy Kap...
BMCBI
2008
120views more  BMCBI 2008»
13 years 7 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...
BMCBI
2008
170views more  BMCBI 2008»
13 years 7 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou