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» Exploration of Evolutionary Relations between Protein Struct...
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BMCBI
2007
117views more  BMCBI 2007»
13 years 9 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
BMCBI
2008
87views more  BMCBI 2008»
13 years 9 months ago
Identification of deleterious non-synonymous single nucleotide polymorphisms using sequence-derived information
Background: As the number of non-synonymous single nucleotide polymorphisms (nsSNPs), also known as single amino acid polymorphisms (SAPs), increases rapidly, computational method...
Jing Hu, Changhui Yan
HT
1987
ACM
14 years 14 days ago
Exploring Representation Problems Using Hypertext
Hypertext is a technology well-suited to exploring different kinds of representational problems. It can be used first as an informal mechanism to describe the attributes of object...
Catherine C. Marshall
BMCBI
2007
105views more  BMCBI 2007»
13 years 9 months ago
Generating confidence intervals on biological networks
Background: In the analysis of networks we frequently require the statistical significance of some network statistic, such as measures of similarity for the properties of interact...
Thomas Thorne, Michael P. H. Stumpf
CORR
2007
Springer
170views Education» more  CORR 2007»
13 years 9 months ago
The structure of verbal sequences analyzed with unsupervised learning techniques
Data mining allows the exploration of sequences of phenomena, whereas one usually tends to focus on isolated phenomena or on the relation between two phenomena. It offers invaluab...
Catherine Recanati, Nicoleta Rogovschi, Youn&egrav...