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BMCBI
2008
13 years 8 months ago
2008
Background: The reconstruction of genetic regulatory networks from microarray gene expression data has been a challenging task in bioinformatics. Various approaches to this proble...
BMCBI
2008
13 years 8 months ago
2008
Background: Recent approaches for predicting the three-dimensional (3D) structure of proteins such as de novo or fold recognition methods mostly rely on simplified energy potentia...
BMCBI
2007
13 years 8 months ago
2007
Background: Identity by descent (IBD) matrix estimation is a central component in mapping of Quantitative Trait Loci (QTL) using variance component models. A large number of algor...
BMCBI
2007
13 years 8 months ago
2007
Background: Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing ...
BMCBI
2007
13 years 8 months ago
2007
Background: Expression Quantitative Trait Locus (eQTL) mapping methods have been used to identify the genetic basis of gene expression variations. To map eQTL, thousands of expres...