Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...
Background: High-throughput genome biological experiments yield large and multifaceted datasets that require flexible and user-friendly analysis tools to facilitate their interpre...
Background: Millions of single nucleotide polymorphisms have been identified as a result of the human genome project and the rapid advance of high throughput genotyping technology...
Wei Yu, Anja Wulf, Tiebin Liu, Muin J. Khoury, Mar...
The bio-ontology community falls into two camps: first we have biology domain experts, who actually hold the knowledge we wish to capture in ontologies; second, we have ontology s...