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BMCBI
2007
165views more  BMCBI 2007»
13 years 9 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
BMCBI
2005
124views more  BMCBI 2005»
13 years 8 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2010
108views more  BMCBI 2010»
13 years 3 months ago
Preferred analysis methods for Affymetrix GeneChips. II. An expanded, balanced, wholly-defined spike-in dataset
Background: Concomitant with the rise in the popularity of DNA microarrays has been a surge of proposed methods for the analysis of microarray data. Fully controlled "spike-i...
Qianqian Zhu, Jeffrey C. Miecznikowski, Marc S. Ha...
BMCBI
2005
77views more  BMCBI 2005»
13 years 8 months ago
Combining Affymetrix microarray results
Background: As the use of microarray technology becomes more prevalent it is not unusual to find several laboratories employing the same microarray technology to identify genes re...
John R. Stevens, R. W. Doerge
MMAS
2010
Springer
13 years 3 months ago
Clustering and Classification through Normalizing Flows in Feature Space
A unified variational methodology is developed for classification and clustering problems, and tested in the classification of tumors from gene expression data. It is based on flu...
J. P. Agnelli, M. Cadeiras, E. G. Tabak, C. V. Tur...