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TCBB
2011
13 years 3 months ago
Probabilistic Analysis of Probe Reliability in Differential Gene Expression Studies with Short Oligonucleotide Arrays
— Probe defects are a major source of noise in gene expression studies. While existing approaches detect noisy probes based on external information such as genomic alignments, we...
Leo Lahti, Laura Elo, Tero Aittokallio, Samuel Kas...
CSB
2005
IEEE
137views Bioinformatics» more  CSB 2005»
14 years 2 months ago
A Learned Comparative Expression Measure for Affymetrix GeneChip DNA Microarrays
Perhaps the most common question that a microarray study can ask is, “Between two given biological conditions, which genes exhibit changed expression levels?” Existing methods...
Will Sheffler, Eli Upfal, John Sedivy, William Sta...
RECOMB
2006
Springer
14 years 9 months ago
A Patient-Gene Model for Temporal Expression Profiles in Clinical Studies
Abstract. Pharmacogenomics and clinical studies that measure the temporal expression levels of patients can identify important pathways and biomarkers that are activated during dis...
Naftali Kaminski, Ziv Bar-Joseph
KDD
2003
ACM
148views Data Mining» more  KDD 2003»
14 years 9 months ago
A highly-usable projected clustering algorithm for gene expression profiles
Projected clustering has become a hot research topic due to its ability to cluster high-dimensional data. However, most existing projected clustering algorithms depend on some cri...
Kevin Y. Yip, David W. Cheung, Michael K. Ng
BMCBI
2004
98views more  BMCBI 2004»
13 years 8 months ago
Incidence of "quasi-ditags" in catalogs generated by Serial Analysis of Gene Expression (SAGE)
Background: Serial Analysis of Gene Expression (SAGE) is a functional genomic technique that quantitatively analyzes the cellular transcriptome. The analysis of SAGE libraries rel...
Sergey V. Anisimov, Alexei A. Sharov