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» Extracting active pathways from gene expression data
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NAR
2011
267views Computer Vision» more  NAR 2011»
13 years 3 months ago
EcoCyc: a comprehensive database of Escherichia coli biology
EcoCyc (http://EcoCyc.org) is a comprehensive model organism database for Escherichia coli K-12 MG1655. From the scientific literature, EcoCyc captures the functions of individual...
Ingrid M. Keseler, Julio Collado-Vides, Alberto Sa...
BMCBI
2008
135views more  BMCBI 2008»
13 years 9 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...
CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
14 years 2 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
BMCBI
2007
95views more  BMCBI 2007»
13 years 8 months ago
Methods for estimating human endogenous retrovirus activities from EST databases
Background: Human endogenous retroviruses (HERVs) are surviving traces of ancient retrovirus infections and now reside within the human DNA. Recently HERV expression has been dete...
Merja Oja, Jaakko Peltonen, Jonas Blomberg, Samuel...
NAR
2007
105views more  NAR 2007»
13 years 8 months ago
Onto-Tools: new additions and improvements in 2006
Onto-Tools is a freely available web-accessible software suite, composed of an annotation database and nine complementary data-mining tools. This article describes a new tool, Ont...
Purvesh Khatri, Calin Voichita, Khalid Kattan, Nad...