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BMCBI
2007
107views more  BMCBI 2007»
13 years 9 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai
BMCBI
2002
214views more  BMCBI 2002»
13 years 8 months ago
Automated modelling of signal transduction networks
Background: Intracellular signal transduction is achieved by networks of proteins and small molecules that transmit information from the cell surface to the nucleus, where they ul...
Martin Steffen, Allegra Petti, John Aach, Patrik D...
BMCBI
2006
118views more  BMCBI 2006»
13 years 8 months ago
Exploration of biological network centralities with CentiBiN
Background: The elucidation of whole-cell regulatory, metabolic, interaction and other biological networks generates the need for a meaningful ranking of network elements. Central...
Björn H. Junker, Dirk Koschützki, Falk S...
BMCBI
2007
151views more  BMCBI 2007»
13 years 8 months ago
Identification of hot regions in protein-protein interactions by sequential pattern mining
Background: Identification of protein interacting sites is an important task in computational molecular biology. As more and more protein sequences are deposited without available...
Chen-Ming Hsu, Chien-Yu Chen, Baw-Jhiune Liu, Chih...
JCDL
2010
ACM
187views Education» more  JCDL 2010»
13 years 10 months ago
Social network document ranking
In search engines, ranking algorithms measure the importance and relevance of documents mainly based on the contents and relationships between documents. User attributes are usual...
Liang Gou, Xiaolong Zhang, Hung-Hsuan Chen, Jung-H...