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RECOMB
2002
Springer
14 years 8 months ago
Phase-independent rhythmic analysis of genome-wide expression patterns
We introduce a model-based analysis technique for extracting and characterizing rhythmic expression pro les from genome-wide DNA microarray hybridization data. These patterns are ...
Christopher James Langmead, Anthony K. Yan, C. Rob...
KDD
2006
ACM
156views Data Mining» more  KDD 2006»
14 years 8 months ago
Discovering significant OPSM subspace clusters in massive gene expression data
Order-preserving submatrixes (OPSMs) have been accepted as a biologically meaningful subspace cluster model, capturing the general tendency of gene expressions across a subset of ...
Byron J. Gao, Obi L. Griffith, Martin Ester, Steve...
BMCBI
2008
138views more  BMCBI 2008»
13 years 8 months ago
Methods for simultaneously identifying coherent local clusters with smooth global patterns in gene expression profiles
Background: The hierarchical clustering tree (HCT) with a dendrogram [1] and the singular value decomposition (SVD) with a dimension-reduced representative map [2] are popular met...
Yin-Jing Tien, Yun-Shien Lee, Han-Ming Wu, Chun-Ho...
ICDM
2008
IEEE
146views Data Mining» more  ICDM 2008»
14 years 2 months ago
Hunting for Coherent Co-clusters in High Dimensional and Noisy Datasets
Clustering problems often involve datasets where only a part of the data is relevant to the problem, e.g., in microarray data analysis only a subset of the genes show cohesive exp...
Meghana Deodhar, Joydeep Ghosh, Gunjan Gupta, Hyuk...
BMCBI
2007
146views more  BMCBI 2007»
13 years 8 months ago
Bayesian hierarchical model for transcriptional module discovery by jointly modeling gene expression and ChIP-chip data
Background: Transcriptional modules (TM) consist of groups of co-regulated genes and transcription factors (TF) regulating their expression. Two high-throughput (HT) experimental ...
Xiangdong Liu, Walter J. Jessen, Siva Sivaganesan,...