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BIOINFORMATICS
2007
74views more  BIOINFORMATICS 2007»
13 years 7 months ago
Simultaneous alignment and annotation of cis-regulatory regions
Genomic transcriptional processes rely heavily on the combinatorial binding of transcription factors on the upstream regions of genes. Analysis and complete characterization of su...
Abha Singh Bais, Steffen Grossmann, Martin Vingron
BMCBI
2005
133views more  BMCBI 2005»
13 years 7 months ago
Ab initio identification of putative human transcription factor binding sites by comparative genomics
Background: Understanding transcriptional regulation of gene expression is one of the greatest challenges of modern molecular biology. A central role in this mechanism is played b...
Davide Corà, Carl Herrmann, Christoph Diete...
BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
In silico identification of NF-kappaB-regulated genes in pancreatic beta-cells
Background: Pancreatic beta-cells are the target of an autoimmune attack in type 1 diabetes mellitus (T1DM). This is mediated in part by cytokines, such as interleukin (IL)-1β an...
Najib Naamane, Jacques van Helden, Decio L. Eiziri...
RECOMB
2007
Springer
14 years 7 months ago
Learning Gene Regulatory Networks via Globally Regularized Risk Minimization
Learning the structure of a gene regulatory network from time-series gene expression data is a significant challenge. Most approaches proposed in the literature to date attempt to ...
Yuhong Guo, Dale Schuurmans
BMCBI
2007
97views more  BMCBI 2007»
13 years 7 months ago
In situ analysis of cross-hybridisation on microarrays and the inference of expression correlation
Background: Microarray co-expression signatures are an important tool for studying gene function and relations between genes. In addition to genuine biological co-expression, corr...
Tineke Casneuf, Yves Van de Peer, Wolfgang Huber