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BMCBI
2007
107views more  BMCBI 2007»
13 years 8 months ago
Linking microarray reporters with protein functions
Background: The analysis of microarray experiments requires accurate and up-to-date functional annotation of the microarray reporters to optimize the interpretation of the biologi...
Stan Gaj, Arie van Erk, Rachel I. M. van Haaften, ...
BMCBI
2006
92views more  BMCBI 2006»
13 years 8 months ago
Similarity-based gene detection: using COGs to find evolutionarily-conserved ORFs
Background: Experimental verification of gene products has not kept pace with the rapid growth of microbial sequence information. However, existing annotations of gene locations c...
Bradford C. Powell, Clyde A. Hutchison III
NAR
2010
107views more  NAR 2010»
13 years 3 months ago
FlyTF: improved annotation and enhanced functionality of the Drosophila transcription factor database
FlyTF (http://www.flytf.org) is a database of computationally predicted and/or experimentally verified site-specific transcription factors (TFs) in the fruit fly Drosophila melano...
Ulrike Pfreundt, Daniel P. James, Susan Tweedie, D...
BMCBI
2007
124views more  BMCBI 2007»
13 years 8 months ago
A high-accuracy consensus map of yeast protein complexes reveals modular nature of gene essentiality
Background: Identifying all protein complexes in an organism is a major goal of systems biology. In the past 18 months, the results of two genome-scale tandem affinity purificatio...
G. Traver Hart, Insuk Lee, Edward M. Marcotte
BMCBI
2005
126views more  BMCBI 2005»
13 years 8 months ago
HomoMINT: an inferred human network based on orthology mapping of protein interactions discovered in model organisms
Background: The application of high throughput approaches to the identification of protein interactions has offered for the first time a glimpse of the global interactome of some ...
Maria Persico, Arnaud Ceol, Caius Gavrila, Robert ...