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BMCBI
2007
166views more  BMCBI 2007»
13 years 8 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang
ICDE
2008
IEEE
124views Database» more  ICDE 2008»
14 years 9 months ago
Mining Approximate Order Preserving Clusters in the Presence of Noise
Subspace clustering has attracted great attention due to its capability of finding salient patterns in high dimensional data. Order preserving subspace clusters have been proven to...
Mengsheng Zhang, Wei Wang 0010, Jinze Liu
BMCBI
2006
98views more  BMCBI 2006»
13 years 8 months ago
Quantitative comparison of EST libraries requires compensation for systematic biases in cDNA generation
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...
Donglin Liu, Joel H. Graber
BMCBI
2005
253views more  BMCBI 2005»
13 years 7 months ago
The Use of Edge-Betweenness Clustering to Investigate Biological Function in Protein Interaction Networks
Background: This paper describes an automated method for finding clusters of interconnected proteins in protein interaction networks and retrieving protein annotations associated ...
Ruth Dunn, Frank Dudbridge, Christopher M. Sanders...
BMCBI
2010
136views more  BMCBI 2010»
13 years 8 months ago
Bias correction and Bayesian analysis of aggregate counts in SAGE libraries
Background: Tag-based techniques, such as SAGE, are commonly used to sample the mRNA pool of an organism's transcriptome. Incomplete digestion during the tag formation proces...
Russell L. Zaretzki, Michael A. Gilchrist, William...