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» Finding Transport Proteins in a General Protein Database
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BMCBI
2005
124views more  BMCBI 2005»
13 years 7 months ago
Probabilistic annotation of protein sequences based on functional classifications
: One of the most evident achievements of bioinformatics is the development of methods that transfer biological knowledge from characterised proteins to uncharacterised sequences. ...
Emmanuel D. Levy, Christos A. Ouzounis, Walter R. ...
BMCBI
2010
163views more  BMCBI 2010»
13 years 7 months ago
Integration of open access literature into the RCSB Protein Data Bank using BioLit
Background: Biological data have traditionally been stored and made publicly available through a variety of on-line databases, whereas biological knowledge has traditionally been ...
Andreas Prlic, Marco A. Martinez, Dimitris Dimitro...
BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
Learning biophysically-motivated parameters for alpha helix prediction
Background: Our goal is to develop a state-of-the-art protein secondary structure predictor, with an intuitive and biophysically-motivated energy model. We treat structure predict...
Blaise Gassend, Charles W. O'Donnell, William Thie...
GECCO
2006
Springer
133views Optimization» more  GECCO 2006»
13 years 11 months ago
String transformation-based Bayesian classification or proteins
We describe a Markov chain Bayesian classification tool, SCS, that can perform data-driven classification of proteins and protein segments. Training data for interesting classific...
Timothy Meekhof, Gary W. Daughdrill, Robert B. Hec...
BMCBI
2005
118views more  BMCBI 2005»
13 years 7 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz