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» Finding Transport Proteins in a General Protein Database
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BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
Statistical power of phylo-HMM for evolutionarily conserved element detection
Background: An important goal of comparative genomics is the identification of functional elements through conservation analysis. Phylo-HMM was recently introduced to detect conse...
Xiaodan Fan, Jun Zhu, Eric E. Schadt, Jun S. Liu
BMCBI
2007
99views more  BMCBI 2007»
13 years 7 months ago
Towards validating the hypothesis of phylogenetic profiling
Background: As the number of fully sequenced genome increases, the need is greater for bioinformatics to predict or annotate genes of a newly sequenced genome. Ever since Eisenber...
Raja Loganantharaj, Mazen Atwi
BMCBI
2005
86views more  BMCBI 2005»
13 years 7 months ago
Chromosomal clustering of a human transcriptome reveals regulatory background
Background: There has been much evidence recently for a link between transcriptional regulation and chromosomal gene order, but the relationship between genomic organization, regu...
Jan H. Vogel, Anja von Heydebreck, Antje Purmann, ...
BMCBI
2004
166views more  BMCBI 2004»
13 years 7 months ago
Gene prediction using the Self-Organizing Map: automatic generation of multiple gene models
Background: Many current gene prediction methods use only one model to represent proteincoding regions in a genome, and so are less likely to predict the location of genes that ha...
Shaun Mahony, James O. McInerney, Terry J. Smith, ...
BMCBI
2010
202views more  BMCBI 2010»
13 years 7 months ago
NeMo: Network Module identification in Cytoscape
Background: As the size of the known human interactome grows, biologists increasingly rely on computational tools to identify patterns that represent protein complexes and pathway...
Corban G. Rivera, Rachit Vakil, Joel S. Bader