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» Finding approximate tandem repeats in genomic sequences
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ALMOB
2006
138views more  ALMOB 2006»
13 years 7 months ago
A combinatorial optimization approach for diverse motif finding applications
Background: Discovering approximately repeated patterns, or motifs, in biological sequences is an important and widely-studied problem in computational molecular biology. Most fre...
Elena Zaslavsky, Mona Singh
BMCBI
2006
101views more  BMCBI 2006»
13 years 7 months ago
How repetitive are genomes?
Background: Genome sequences vary strongly in their repetitiveness and the causes for this are still debated. Here we propose a novel measure of genome repetitiveness, the index o...
Bernhard Haubold, Thomas Wiehe
RECOMB
2006
Springer
14 years 8 months ago
Sorting by Weighted Reversals, Transpositions, and Inverted Transpositions
Abstract. During evolution, genomes are subject to genome rearrangements that alter the ordering and orientation of genes on the chromosomes. If a genome consists of a single chrom...
Martin Bader, Enno Ohlebusch
BMCBI
2006
150views more  BMCBI 2006»
13 years 7 months ago
CGAT: a comparative genome analysis tool for visualizing alignments in the analysis of complex evolutionary changes between clos
Background: The recent accumulation of closely related genomic sequences provides a valuable resource for the elucidation of the evolutionary histories of various organisms. Howev...
Ikuo Uchiyama, Toshio Higuchi, Ichizo Kobayashi
BMCBI
2007
113views more  BMCBI 2007»
13 years 7 months ago
PILER-CR: Fast and accurate identification of CRISPR repeats
Background: Sequencing of prokaryotic genomes has recently revealed the presence of CRISPR elements: short, highly conserved repeats separated by unique sequences of similar lengt...
Robert C. Edgar