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» Fixed-Parameter Algorithms in Phylogenetics
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BMCBI
2005
93views more  BMCBI 2005»
13 years 8 months ago
Multiple sequence alignment accuracy and evolutionary distance estimation
Background: Sequence alignment is a common tool in bioinformatics and comparative genomics. It is generally assumed that multiple sequence alignment yields better results than pai...
Michael S. Rosenberg
BMCBI
2006
110views more  BMCBI 2006»
13 years 8 months ago
CpGcluster: a distance-based algorithm for CpG-island detection
Background: Despite their involvement in the regulation of gene expression and their importance as genomic markers for promoter prediction, no objective standard exists for defini...
Michael Hackenberg, Christopher Previti, Pedro Lui...
RECOMB
2008
Springer
14 years 8 months ago
A Fast, Alignment-Free, Conservation-Based Method for Transcription Factor Binding Site Discovery
As an increasing number of eukaryotic genomes are being sequenced, comparative studies aimed at detecting regulatory elements in intergenic sequences are becoming more prevalent. M...
Raluca Gordân, Leelavati Narlikar, Alexander...
PRIB
2009
Springer
100views Bioinformatics» more  PRIB 2009»
14 years 3 months ago
Evidence-Based Clustering of Reads and Taxonomic Analysis of Metagenomic Data
Abstract. The rapidly emerging field of metagenomics seeks to examine the genomic content of communities of organisms to understand their roles and interactions in an ecosystem. I...
Gianluigi Folino, Fabio Gori, Mike S. M. Jetten, E...
RECOMB
2007
Springer
14 years 8 months ago
Beyond Galled Trees - Decomposition and Computation of Galled Networks
Reticulate networks are a type of phylogenetic network that are used to represent reticulate evolution involving hybridization, horizontal gene transfer or recombination. The simpl...
Daniel H. Huson, Tobias H. Klöpper