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BMCBI
2006
137views more  BMCBI 2006»
15 years 4 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BMCBI
2006
114views more  BMCBI 2006»
15 years 4 months ago
Epigenetic acquisition of inducibility of type III cytotoxicity in P. aeruginosa
Background: Pseudomonas aeruginosa, an opportunistic pathogen, is often encountered in chronic lung diseases such as cystic fibrosis or chronic obstructive pneumonia, as well as a...
Didier Filopon, Annabelle Mérieau, Gilles B...
JCB
2006
185views more  JCB 2006»
15 years 4 months ago
A Probabilistic Methodology for Integrating Knowledge and Experiments on Biological Networks
Biological systems are traditionally studied by focusing on a specific subsystem, building an intuitive model for it, and refining the model using results from carefully designed ...
Irit Gat-Viks, Amos Tanay, Daniela Raijman, Ron Sh...
JMLR
2006
169views more  JMLR 2006»
15 years 4 months ago
Bayesian Network Learning with Parameter Constraints
The task of learning models for many real-world problems requires incorporating domain knowledge into learning algorithms, to enable accurate learning from a realistic volume of t...
Radu Stefan Niculescu, Tom M. Mitchell, R. Bharat ...
MICRO
2008
IEEE
137views Hardware» more  MICRO 2008»
15 years 4 months ago
Verification of chip multiprocessor memory systems using a relaxed scoreboard
Verification of chip multiprocessor memory systems remains challenging. While formal methods have been used to validate protocols, simulation is still the dominant method used to ...
Ofer Shacham, Megan Wachs, Alex Solomatnikov, Amin...
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