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» From Cardiac Cells to Genetic Regulatory Networks
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BMCBI
2006
110views more  BMCBI 2006»
13 years 7 months ago
Modelling the network of cell cycle transcription factors in the yeast Saccharomyces cerevisiae
Background: Reverse-engineering regulatory networks is one of the central challenges for computational biology. Many techniques have been developed to accomplish this by utilizing...
Shawn Cokus, Sherri Rose, David Haynor, Niels Gr&o...
BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
An improved map of conserved regulatory sites for Saccharomyces cerevisiae
Background: The regulatory map of a genome consists of the binding sites for proteins that determine the transcription of nearby genes. An initial regulatory map for S. cerevisiae...
Kenzie D. MacIsaac, Ting Wang, D. Benjamin Gordon,...
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
A model-based optimization framework for the inference of regulatory interactions using time-course DNA microarray expression da
Background: Proteins are the primary regulatory agents of transcription even though mRNA expression data alone, from systems like DNA microarrays, are widely used. In addition, th...
Reuben Thomas, Carlos J. Paredes, Sanjay Mehrotra,...
BIBM
2008
IEEE
145views Bioinformatics» more  BIBM 2008»
14 years 2 months ago
Meta Analysis of Microarray Data Using Gene Regulation Pathways
Using microarray technology for genetic analysis in biological experiments requires computationally intensive tools to interpret results. The main objective here is to develop a â...
Saira Ali Kazmi, Yoo-Ah Kim, Baikang Pei, Ravi Nor...
BMCBI
2010
110views more  BMCBI 2010»
13 years 7 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...