23119 search results - page 4523 / 4624 » From Domain to Requirements |
153
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BMCBI
2008
15 years 6 months ago
2008
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...
160
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BMCBI
2008
2008
Relating gene expression data on two-component systems to functional annotations in Escherichia coli
15 years 6 months ago
Background: Obtaining physiological insights from microarray experiments requires computational techniques that relate gene expression data to functional information. Traditionall...
154
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BMCBI
2008
15 years 6 months ago
2008
Background: Non-homology based methods such as phylogenetic profiles are effective for predicting functional relationships between proteins with no considerable sequence or struct...
151
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BMCBI
2007
15 years 6 months ago
2007
Background: Chromatin immunoprecipitation combined with DNA microarrays (ChIP-chip) is a high-throughput assay for DNA-protein-binding or post-translational chromatin/histone modi...
128
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BMCBI
2008
15 years 6 months ago
2008
Background: There are several situations in population biology research where simulating DNA sequences is useful. Simulation of biological populations under different evolutionary...