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BMCBI
2008
135views more  BMCBI 2008»
13 years 9 months ago
Ab-origin: an enhanced tool to identify the sourcing gene segments in germline for rearranged antibodies
Background: In the adaptive immune system, variable regions of immunoglobulin (IG) are encoded by random recombination of variable (V), diversity (D), and joining (J) gene segment...
Xiaojing Wang, Di Wu, SiYuan Zheng, Jing Sun, Lin ...
BMCBI
2008
208views more  BMCBI 2008»
13 years 9 months ago
GraphFind: enhancing graph searching by low support data mining techniques
Background: Biomedical and chemical databases are large and rapidly growing in size. Graphs naturally model such kinds of data. To fully exploit the wealth of information in these...
Alfredo Ferro, Rosalba Giugno, Misael Mongiov&igra...
BMCBI
2008
153views more  BMCBI 2008»
13 years 9 months ago
Improved general regression network for protein domain boundary prediction
Background: Protein domains present some of the most useful information that can be used to understand protein structure and functions. Recent research on protein domain boundary ...
Paul D. Yoo, Abdur R. Sikder, Bing Bing Zhou, Albe...
BMCBI
2008
106views more  BMCBI 2008»
13 years 9 months ago
Ontology Design Patterns for bio-ontologies: a case study on the Cell Cycle Ontology
Background: Bio-ontologies are key elements of knowledge management in bioinformatics. Rich and rigorous bio-ontologies should represent biological knowledge with high fidelity an...
Mikel Egaña Aranguren, Erick Antezana, Mart...
BMCBI
2005
111views more  BMCBI 2005»
13 years 9 months ago
Improving interoperability between microbial information and sequence databases
Background: Biological resources are essential tools for biomedical research. Their availability is promoted through on-line catalogues. Common Access to Biological Resources and ...
Paolo Romano, Peter Dawyndt, Francesca Piersigilli...