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» From genomics to chemical genomics: new developments in KEGG
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ISBI
2011
IEEE
12 years 11 months ago
Boosting power to detect genetic associations in imaging using multi-locus, genome-wide scans and ridge regression
Most algorithms used for imaging genetics examine statistical effects of each individual genetic variant, one at a time. We developed a new approach, based on ridge regression, to...
Omid Kohannim, Derrek P. Hibar, Jason L. Stein, Ne...
NAR
2010
115views more  NAR 2010»
13 years 2 months ago
ChimerDB 2.0 - a knowledgebase for fusion genes updated
Chromosome translocations and gene fusions are frequent events in the human genome and have been found to cause diverse types of tumor. ChimerDB is a knowledgebase of fusion genes...
Pora Kim, Suhyeon Yoon, Namshin Kim, Sanghyun Lee,...
BMCBI
2007
152views more  BMCBI 2007»
13 years 7 months ago
A cross-species alignment tool (CAT)
Background: The main two sorts of automatic gene annotation frameworks are ab initio and alignment-based, the latter splitting into two sub-groups. The first group is used for int...
Heng Li, Liang Guan, Tao Liu, Yiran Guo, Wei-Mou Z...
BMCBI
2008
57views more  BMCBI 2008»
13 years 7 months ago
A novel method for high accuracy sumoylation site prediction from protein sequences
Background: Protein sumoylation is an essential dynamic, reversible post translational modification that plays a role in dozens of cellular activities, especially the regulation o...
Jialin Xu, Yun He, Boqin Qiang, Jiangang Yuan, Xia...
BMCBI
2006
119views more  BMCBI 2006»
13 years 7 months ago
Hidden Markov Model Variants and their Application
Markov statistical methods may make it possible to develop an unsupervised learning process that can automatically identify genomic structure in prokaryotes in a comprehensive way...
Stephen Winters-Hilt