Numerous genetic variations have been found to be related to human diseases. Significant portion of those affect the drug response as well by changing the protein structure and fu...
Jin Ok Yang, Sangho Oh, Gunhwan Ko, Seong-Jin Park...
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Automatic tools for finding software errors require a set of specifications before they can check code: if they do not know what to check, they cannot find bugs. This paper presen...
Ted Kremenek, Paul Twohey, Godmar Back, Andrew Y. ...
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
Ya Zhang, John-Marc Chandonia, Chris H. Q. Ding, S...
Background: Currently there is a strong need for methods that help to obtain an accurate description of protein interfaces in order to be able to understand the principles that go...
Joan Teyra, Andreas Doms, Michael Schroeder, M. Te...