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NAR
2011
227views Computer Vision» more  NAR 2011»
13 years 4 months ago
VnD: a structure-centric database of disease-related SNPs and drugs
Numerous genetic variations have been found to be related to human diseases. Significant portion of those affect the drug response as well by changing the protein structure and fu...
Jin Ok Yang, Sangho Oh, Gunhwan Ko, Seong-Jin Park...
BMCBI
2008
149views more  BMCBI 2008»
13 years 9 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
OSDI
2006
ACM
14 years 9 months ago
From Uncertainty to Belief: Inferring the Specification Within
Automatic tools for finding software errors require a set of specifications before they can check code: if they do not know what to check, they cannot find bugs. This paper presen...
Ted Kremenek, Paul Twohey, Godmar Back, Andrew Y. ...
BMCBI
2005
97views more  BMCBI 2005»
13 years 9 months ago
Comparative mapping of sequence-based and structure-based protein domains
Background: Protein domains have long been an ill-defined concept in biology. They are generally described as autonomous folding units with evolutionary and functional independenc...
Ya Zhang, John-Marc Chandonia, Chris H. Q. Ding, S...
BMCBI
2006
120views more  BMCBI 2006»
13 years 9 months ago
SCOWLP: a web-based database for detailed characterization and visualization of protein interfaces
Background: Currently there is a strong need for methods that help to obtain an accurate description of protein interfaces in order to be able to understand the principles that go...
Joan Teyra, Andreas Doms, Michael Schroeder, M. Te...