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» Functional topology in a network of protein interactions
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BMCBI
2006
108views more  BMCBI 2006»
13 years 7 months ago
SPIDer: Saccharomyces protein-protein interaction database
Background: Since proteins perform their functions by interacting with one another and with other biomolecules, reconstructing a map of the protein-protein interactions of a cell,...
Xiaomei Wu, Lei Zhu, Jie Guo, Cong Fu, Hongjun Zho...
RECOMB
2005
Springer
14 years 7 months ago
Pairwise Local Alignment of Protein Interaction Networks Guided by Models of Evolution
Abstract. With ever increasing amount of available data on protein-protein interaction (PPI) networks and research revealing that these networks evolve at a modular level, discover...
Mehmet Koyutürk, Ananth Grama, Wojciech Szpan...
BIBE
2006
IEEE
160views Bioinformatics» more  BIBE 2006»
14 years 1 months ago
Methods for Random Modularization of Biological Networks
— Biological networks are formalized summaries of our knowledge about interactions among biological system components, like genes, proteins, or metabolites. From their global top...
Zachary M. Saul, Vladimir Filkov
BMCBI
2011
12 years 11 months ago
MINE: Module Identification in NEtworks
Background: Graphical models of network associations are useful for both visualizing and integrating multiple types of association data. Identifying modules, or groups of function...
Kahn Rhrissorrakrai, Kristin C. Gunsalus
BMCBI
2007
166views more  BMCBI 2007»
13 years 7 months ago
PathFinder: mining signal transduction pathway segments from protein-protein interaction networks
Background: A Signal transduction pathway is the chain of processes by which a cell converts an extracellular signal into a response. In most unicellular organisms, the number of ...
Gürkan Bebek, Jiong Yang