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131
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AOSD
2008
ACM
15 years 6 months ago
"Program, enhance thyself!": demand-driven pattern-oriented program enhancement
Program enhancement refers to adding new functionality to an existing program. We argue that repetitive program enhancement tasks can be expressed as patterns, and that the applic...
Eli Tilevich, Godmar Back
140
Voted
BMCBI
2010
112views more  BMCBI 2010»
15 years 4 months ago
PhenoFam-gene set enrichment analysis through protein structural information
Background: With the current technological advances in high-throughput biology, the necessity to develop tools that help to analyse the massive amount of data being generated is e...
Maciej Paszkowski-Rogacz, Mikolaj Slabicki, M. Ter...
BMCBI
2010
139views more  BMCBI 2010»
15 years 4 months ago
PoGO: Prediction of Gene Ontology terms for fungal proteins
Background: Automated protein function prediction methods are the only practical approach for assigning functions to genes obtained from model organisms. Many of the previously re...
Jaehee Jung, Gangman Yi, Serenella A. Sukno, Micha...
BMCBI
2010
136views more  BMCBI 2010»
15 years 4 months ago
Protein structure analysis of mutations causing inheritable diseases. An e-Science approach with life scientist friendly interfa
Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
158
Voted
BMCBI
2002
126views more  BMCBI 2002»
15 years 4 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy