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» GASSST: global alignment short sequence search tool
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NAR
2006
62views more  NAR 2006»
13 years 7 months ago
siVirus: web-based antiviral siRNA design software for highly divergent viral sequences
siVirus (http://siVirus.RNAi.jp/) is a web-based online software system that provides efficient short interfering RNA (siRNA) design for antiviral RNA interference (RNAi). siVirus...
Yuki Naito, Kumiko Ui-Tei, Toru Nishikawa, Yutaka ...
BMCBI
2006
143views more  BMCBI 2006»
13 years 7 months ago
IsoSVM - Distinguishing isoforms and paralogs on the protein level
Background: Recent progress in cDNA and EST sequencing is yielding a deluge of sequence data. Like database search results and proteome databases, this data gives rise to inferred...
Michael Spitzer, Stefan Lorkowski, Paul Cullen, Al...
BMCBI
2005
152views more  BMCBI 2005»
13 years 7 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
NAR
2010
115views more  NAR 2010»
13 years 2 months ago
ChimerDB 2.0 - a knowledgebase for fusion genes updated
Chromosome translocations and gene fusions are frequent events in the human genome and have been found to cause diverse types of tumor. ChimerDB is a knowledgebase of fusion genes...
Pora Kim, Suhyeon Yoon, Namshin Kim, Sanghyun Lee,...
BMCBI
2005
119views more  BMCBI 2005»
13 years 7 months ago
The distance-profile representation and its application to detection of distantly related protein families
Background: Detecting homology between remotely related protein families is an important problem in computational biology since the biological properties of uncharacterized protei...
Chin-Jen Ku, Golan Yona