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BMCBI
2006
180views more  BMCBI 2006»
13 years 6 months ago
The Gaggle: An open-source software system for integrating bioinformatics software and data sources
Background: Systems biologists work with many kinds of data, from many different sources, using a variety of software tools. Each of these tools typically excels at one type of an...
Paul T. Shannon, David J. Reiss, Richard Bonneau, ...
BMCBI
2007
168views more  BMCBI 2007»
13 years 6 months ago
Bayesian model-based inference of transcription factor activity
Background: In many approaches to the inference and modeling of regulatory interactions using microarray data, the expression of the gene coding for the transcription factor is co...
Simon Rogers, Raya Khanin, Mark Girolami
BMCBI
2007
151views more  BMCBI 2007»
13 years 6 months ago
The Genopolis Microarray Database
Background: Gene expression databases are key resources for microarray data management and analysis and the importance of a proper annotation of their content is well understood. ...
Andrea Splendiani, Marco Brandizi, Gael Even, Otta...
BIBE
2007
IEEE
124views Bioinformatics» more  BIBE 2007»
14 years 29 days ago
Finding Cancer-Related Gene Combinations Using a Molecular Evolutionary Algorithm
—High-throughput data such as microarrays make it possible to investigate the molecular-level mechanism of cancer more efficiently. Computational methods boost the microarray ana...
Chan-Hoon Park, Soo-Jin Kim, Sun Kim, Dong-Yeon Ch...
JCB
2007
130views more  JCB 2007»
13 years 6 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey