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BMCBI
2011
12 years 11 months ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson
BMCBI
2007
106views more  BMCBI 2007»
13 years 7 months ago
Modeling SAGE tag formation and its effects on data interpretation within a Bayesian framework
Background: Serial Analysis of Gene Expression (SAGE) is a high-throughput method for inferring mRNA expression levels from the experimentally generated sequence based tags. Stand...
Michael A. Gilchrist, Hong Qin, Russell L. Zaretzk...
JNW
2008
167views more  JNW 2008»
13 years 7 months ago
Analyzing the ENRON Communication Network Using Agent-Based Simulation
Agent-based modeling, simulation, and network analysis approaches are one of the emergent techniques among soft computing literature. This paper presents an agent-based model for a...
Shinako Matsuyama, Takao Terano
ISMB
1997
13 years 9 months ago
Functional Prediction of B. subtilis Genes from Their Regulatory Sequences
In bacterial cells, gene expression is regulated by multiple sigma factors, each of which has its promoter specificity, according to their conditions. Thus, if we can discriminate...
Tetsushi Yada, Yasushi Totoki, Takahiro Ishii, Ken...
BMCBI
2008
120views more  BMCBI 2008»
13 years 7 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...