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» Gene Expression Clustering with Functional Mixture Models
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CIBCB
2005
IEEE
13 years 9 months ago
A Transcriptional Approach to Gene Clustering
— We present an integrative method for clustering coregulated genes and elucidating their underlying regulatory mechanisms. We use multi-state partition functions and thermodynam...
Ilias Tagkopoulos
BMCBI
2006
165views more  BMCBI 2006»
13 years 7 months ago
Validation and functional annotation of expression-based clusters based on gene ontology
Background: The biological interpretation of large-scale gene expression data is one of the paramount challenges in current bioinformatics. In particular, placing the results in t...
Ralf Steuer, Peter Humburg, Joachim Selbig
BMCBI
2007
134views more  BMCBI 2007»
13 years 8 months ago
Nearest Neighbor Networks: clustering expression data based on gene neighborhoods
Background: The availability of microarrays measuring thousands of genes simultaneously across hundreds of biological conditions represents an opportunity to understand both indiv...
Curtis Huttenhower, Avi I. Flamholz, Jessica N. La...
APBC
2004
138views Bioinformatics» more  APBC 2004»
13 years 9 months ago
Whole-Genome Functional Classification of Genes by Latent Semantic Analysis on Microarray Data
Quantitative simultaneous monitoring of the expression levels of thousands of genes under various experimental conditions is now possible using microarray experiments. The resulti...
See-Kiong Ng, Zexuan Zhu, Yew-Soon Ong