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» Gene Level Concurrency in Genetic Algorithms
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RECOMB
2004
Springer
14 years 7 months ago
Comparing in situ mRNA expression patterns of drosophila embryos
In situ staining of a target mRNA at several time points during the development of a D. melanogaster embryo gives one a detailed spatio-temporal view of the expression pattern of ...
Hanchuan Peng, Eugene W. Myers
BMCBI
2008
99views more  BMCBI 2008»
13 years 7 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...
KDD
2006
ACM
156views Data Mining» more  KDD 2006»
14 years 7 months ago
Discovering significant OPSM subspace clusters in massive gene expression data
Order-preserving submatrixes (OPSMs) have been accepted as a biologically meaningful subspace cluster model, capturing the general tendency of gene expressions across a subset of ...
Byron J. Gao, Obi L. Griffith, Martin Ester, Steve...
BIODATAMINING
2008
140views more  BIODATAMINING 2008»
13 years 7 months ago
Modeling gene-by-environment interaction in comorbid depression with alcohol use disorders via an integrated bioinformatics appr
Background: Comorbidity of Major Depressive Disorder (depression) and Alcohol Use Disorders (AUD) is well documented. Depression, AUD, and the comorbidity of depression with AUD s...
Richard C. McEachin, Benjamin J. Keller, Erika F. ...
BMCBI
2007
95views more  BMCBI 2007»
13 years 7 months ago
Haplotype-based score test for linkage in nuclear families
Background: To look for genetic linkage between angiotensin-I converting enzyme(ACE) gene and hypertension in a Korean adolescent cohort, we developed a powerful test using the co...
Chung Mo Nam, Dae Ryong Kang, Jinheum Kim