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BMCBI
2006
119views more  BMCBI 2006»
13 years 7 months ago
LS-NMF: A modified non-negative matrix factorization algorithm utilizing uncertainty estimates
Background: Non-negative matrix factorisation (NMF), a machine learning algorithm, has been applied to the analysis of microarray data. A key feature of NMF is the ability to iden...
Guoli Wang, Andrew V. Kossenkov, Michael F. Ochs
BMCBI
2007
130views more  BMCBI 2007»
13 years 7 months ago
Differential analysis for high density tiling microarray data
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
BMCBI
2004
113views more  BMCBI 2004»
13 years 7 months ago
Influence of microarrays experiments missing values on the stability of gene groups by hierarchical clustering
Background: Microarray technologies produced large amount of data. The hierarchical clustering is commonly used to identify clusters of co-expressed genes. However, microarray dat...
Alexandre G. de Brevern, Serge A. Hazout, Alain Ma...
BMCBI
2007
111views more  BMCBI 2007»
13 years 7 months ago
Novel definition files for human GeneChips based on GeneAnnot
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
Francesco Ferrari, Stefania Bortoluzzi, Alessandro...
BMCBI
2010
98views more  BMCBI 2010»
13 years 7 months ago
A semi-nonparametric mixture model for selecting functionally consistent proteins
Background: High-throughput technologies have led to a new era of proteomics. Although protein microarray experiments are becoming more common place there are a variety of experim...
Lianbo Yu, R. W. Doerge