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» Gene finding in novel genomes
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BMCBI
2007
102views more  BMCBI 2007»
13 years 8 months ago
Identification of homologs in insignificant blast hits by exploiting extrinsic gene properties
Background: Homology is a key concept in both evolutionary biology and genomics. Detection of homology is crucial in fields like the functional annotation of protein sequences and...
Jos Boekhorst, Berend Snel
EVOW
2010
Springer
13 years 6 months ago
Finding Gapped Motifs by a Novel Evolutionary Algorithm
Background: Identifying approximately repeated patterns, or motifs, in DNA sequences from a set of co-regulated genes is an important step towards deciphering the complex gene reg...
Chengwei Lei, Jianhua Ruan
TREC
2003
13 years 9 months ago
Methods for Accurate Retrieval of MEDLINE Citations in Functional Genomics
The lack of discipline and consistency in gene naming poses a formidable challenge to researchers in locating relevant information sources in the genomics literature. The research...
Mehmet Kayaalp, Alan R. Aronson, Susanne M. Humphr...
BMCBI
2006
169views more  BMCBI 2006»
13 years 8 months ago
Finding biological process modifications in cancer tissues by mining gene expression correlations
Background: Through the use of DNA microarrays it is now possible to obtain quantitative measurements of the expression of thousands of genes from a biological sample. This techno...
Giacomo Gamberoni, Sergio Storari, Stefano Volinia
CSB
2005
IEEE
109views Bioinformatics» more  CSB 2005»
14 years 1 months ago
Patterns of Gene Deletion following Genome Duplication in Yeast
Whole genome duplication (WGD) is followed by massive duplicate deletion that reorganizes gene adjacencies. We compare the deletion patterns and adjacency reorganization following...
Jake K. Byrnes, Wen-Hsiung Li