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» Gene functional classification from heterogeneous data
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BMCBI
2007
78views more  BMCBI 2007»
13 years 10 months ago
Improved human disease candidate gene prioritization using mouse phenotype
Background: The majority of common diseases are multi-factorial and modified by genetically and mechanistically complex polygenic interactions and environmental factors. High-thro...
Jing Chen, Huan Xu, Bruce J. Aronow, Anil G. Jegga
RECOMB
2009
Springer
14 years 4 months ago
Inferring the Recent Duplication History of a Gene Cluster
Abstract. Much important evolutionary activity occurs in gene clusters, where a copy of a gene may be free to evolve new functions. Computational methods to extract evolutionary in...
Giltae Song, Louxin Zhang, Tomás Vinar, Web...
ICML
2010
IEEE
13 years 8 months ago
Heterogeneous Continuous Dynamic Bayesian Networks with Flexible Structure and Inter-Time Segment Information Sharing
Classical dynamic Bayesian networks (DBNs) are based on the homogeneous Markov assumption and cannot deal with heterogeneity and non-stationarity in temporal processes. Various ap...
Frank Dondelinger, Sophie Lebre, Dirk Husmeier
BMCBI
2010
183views more  BMCBI 2010»
13 years 7 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...
BMCBI
2011
13 years 5 months ago
A novel approach to the clustering of microarray data via nonparametric density estimation
Background: Cluster analysis is a crucial tool in several biological and medical studies dealing with microarray data. Such studies pose challenging statistical problems due to di...
Riccardo De Bin, Davide Risso