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» Gene set analysis using principal components
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BMCBI
2010
183views more  BMCBI 2010»
13 years 8 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...
BMCBI
2007
122views more  BMCBI 2007»
13 years 10 months ago
Dissecting complex transcriptional responses using pathway-level scores based on prior information
Background: The genomewide pattern of changes in mRNA expression measured using DNA microarrays is typically a complex superposition of the response of multiple regulatory pathway...
Harmen J. Bussemaker, Lucas D. Ward, André ...
BMCBI
2006
170views more  BMCBI 2006»
13 years 10 months ago
Biclustering of gene expression data by non-smooth non-negative matrix factorization
Background: The extended use of microarray technologies has enabled the generation and accumulation of gene expression datasets that contain expression levels of thousands of gene...
Pedro Carmona-Saez, Roberto D. Pascual-Marqui, Fra...
IJBRA
2007
97views more  IJBRA 2007»
13 years 10 months ago
Structural Risk Minimisation based gene expression profiling analysis
: For microarray based cancer classification, feature selection is a common method for improving classifier generalisation. Most wrapper methods use cross validation methods to eva...
Xue-wen Chen, Byron Gerlach, Dechang Chen, ZhenQiu...
IV
2007
IEEE
160views Visualization» more  IV 2007»
14 years 5 months ago
Targeted Projection Pursuit for Interactive Exploration of High- Dimensional Data Sets
High-dimensional data is, by its nature, difficult to visualise. Many current techniques involve reducing the dimensionality of the data, which results in a loss of information. ...
Joe Faith