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BMCBI
2007
144views more  BMCBI 2007»
15 years 2 months ago
Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...
BMCBI
2010
72views more  BMCBI 2010»
15 years 2 months ago
Phylogenetic representativeness: a new method for evaluating taxon sampling in evolutionary studies
Background: Taxon sampling is a major concern in phylogenetic studies. Incomplete, biased, or improper taxon sampling can lead to misleading results in reconstructing evolutionary...
Federico Plazzi, Ronald R. Ferrucci, Marco Passamo...
COMPLIFE
2006
Springer
15 years 6 months ago
Beating the Noise: New Statistical Methods for Detecting Signals in MALDI-TOF Spectra Below Noise Level
Background: The computer-assisted detection of small molecules by mass spectrometry in biological samples provides a snapshot of thousands of peptides, protein fragments and prote...
Tim O. F. Conrad, Alexander Leichtle, Andre Hageh&...
CSB
2005
IEEE
130views Bioinformatics» more  CSB 2005»
15 years 8 months ago
Integration of RNA Search methods for Identifying Novel Riboswitch Patterns in Eukaryotes
Riboswitches are RNA genetic control elements that were recently discovered in living cells. To regulate gene expression, they utilize a unique mechanism whereby small molecules b...
Adaya N. Cohen, Klara Kedem, Michal Shapira, Danny...
PRIB
2009
Springer
100views Bioinformatics» more  PRIB 2009»
15 years 9 months ago
Evidence-Based Clustering of Reads and Taxonomic Analysis of Metagenomic Data
Abstract. The rapidly emerging field of metagenomics seeks to examine the genomic content of communities of organisms to understand their roles and interactions in an ecosystem. I...
Gianluigi Folino, Fabio Gori, Mike S. M. Jetten, E...