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BMCBI
2008
108views more  BMCBI 2008»
15 years 6 months ago
A nonparametric model for quality control of database search results in shotgun proteomics
Background: Analysis of complex samples with tandem mass spectrometry (MS/MS) has become routine in proteomic research. However, validation of database search results creates a bo...
Jiyang Zhang, Jianqi Li, Xin Liu, Hongwei Xie, Yun...
BMCBI
2007
109views more  BMCBI 2007»
15 years 6 months ago
Computational RNA secondary structure design: empirical complexity and improved methods
Background: We investigate the empirical complexity of the RNA secondary structure design problem, that is, the scaling of the typical difficulty of the design task for various cl...
Rosalía Aguirre-Hernández, Holger H....
BMCBI
2008
115views more  BMCBI 2008»
15 years 6 months ago
BioGraphE: high-performance bionetwork analysis using the Biological Graph Environment
Background: Graphs and networks are common analysis representations for biological systems. Many traditional graph algorithms such as k-clique, k-coloring, and subgraph matching h...
George Chin Jr., Daniel G. Chavarría-Mirand...
COMGEO
2010
ACM
15 years 6 months ago
Approximation algorithm for the kinetic robust K-center problem
Clustering is an important problem and has numerous applications. In this paper we consider an important clustering problem, called the k-center problem. We are given a discrete p...
Sorelle A. Friedler, David M. Mount
CONSTRAINTS
2010
126views more  CONSTRAINTS 2010»
15 years 6 months ago
Lexicographically-ordered constraint satisfaction problems
Abstract. We describe a simple CSP formalism for handling multi-attribute preference problems with hard constraints, one that combines hard constraints and preferences so the two a...
Eugene C. Freuder, Robert Heffernan, Richard J. Wa...
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