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BMCBI
2007
155views more  BMCBI 2007»
13 years 7 months ago
ProMEX: a mass spectral reference database for proteins and protein phosphorylation sites
Background: In the last decade, techniques were established for the large scale genome-wide analysis of proteins, RNA, and metabolites, and database solutions have been developed ...
Jan Hummel, Michaela Niemann, Stefanie Wienkoop, W...
BMCBI
2010
95views more  BMCBI 2010»
13 years 7 months ago
Identifying main effects and epistatic interactions from large-scale SNP data via adaptive group Lasso
Background: Single nucleotide polymorphism (SNP) based association studies aim at identifying SNPs associated with phenotypes, for example, complex diseases. The associated SNPs m...
Can Yang, Xiang Wan, Qiang Yang, Hong Xue, Weichua...
BMCBI
2008
125views more  BMCBI 2008»
13 years 7 months ago
MAID : An effect size based model for microarray data integration across laboratories and platforms
Background: Gene expression profiling has the potential to unravel molecular mechanisms behind gene regulation and identify gene targets for therapeutic interventions. As microarr...
Ivan Borozan, Limin Chen, Bryan Paeper, Jenny E. H...
BMCBI
2006
109views more  BMCBI 2006»
13 years 7 months ago
An integrated system for genetic analysis
Background: Large-scale genetic mapping projects require data management systems that can handle complex phenotypes and detect and correct high-throughput genotyping errors, yet a...
Simon Fiddy, David Cattermole, Dong Xie, Xiao Yuan...
BMCBI
2011
13 years 2 months ago
Removing Noise From Pyrosequenced Amplicons
Background: In many environmental genomics applications a homologous region of DNA from a diverse sample is first amplified by PCR and then sequenced. The next generation sequenci...
Christopher Quince, Anders Lanzén, Russell ...