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» Genome Alignments Using MPI-LAGAN
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BMCBI
2010
150views more  BMCBI 2010»
13 years 8 months ago
DeltaProt: a software toolbox for comparative genomics
Background: Statistical bioinformatics is the study of biological data sets obtained by new micro-technologies by means of proper statistical methods. For a better understanding o...
Steinar Thorvaldsen, Tor Flå, Nils Willassen
RECOMB
2008
Springer
14 years 9 months ago
A Fast, Alignment-Free, Conservation-Based Method for Transcription Factor Binding Site Discovery
As an increasing number of eukaryotic genomes are being sequenced, comparative studies aimed at detecting regulatory elements in intergenic sequences are becoming more prevalent. M...
Raluca Gordân, Leelavati Narlikar, Alexander...
BMCBI
2011
13 years 6 days ago
Combinatorial analysis and algorithms for quasispecies reconstruction using next-generation sequencing
Background: Next-generation sequencing (NGS) offers a unique opportunity for high-throughput genomics and has potential to replace Sanger sequencing in many fields, including de-n...
Mattia C. F. Prosperi, Luciano Prosperi, Alessandr...
BMCBI
2007
233views more  BMCBI 2007»
13 years 8 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
NAR
2011
208views Computer Vision» more  NAR 2011»
12 years 11 months ago
The UCSC Genome Browser database: update 2011
The University of California, Santa Cruz Genome Browser (http://genome.ucsc.edu) offers online access to a database of genomic sequence and annotation data for a wide variety of o...
Pauline A. Fujita, Brooke L. Rhead, Ann S. Zweig, ...