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BIBM
2010
IEEE
151views Bioinformatics» more  BIBM 2010»
13 years 5 months ago
Probabilistic topic modeling for genomic data interpretation
Recently, the concept of a species containing both core and distributed genes, known as the supra- or pangenome theory, has been introduced. In this paper, we aim to develop a new ...
Xin Chen, Xiaohua Hu, Xiajiong Shen, Gail Rosen
CIKM
2008
Springer
13 years 9 months ago
Passage relevance models for genomics search
We present a passage relevance model for integrating syntactic and semantic evidence of biomedical concepts and topics using a probabilistic graphical model. Component models of t...
Jay Urbain, Ophir Frieder, Nazli Goharian
ISMB
1996
13 years 8 months ago
The Mathematical Model of Subtractive Hybridization and Its Practical Application
A novel theory of subtractive hybridization including (or based on) the kinetic model of this process was proposed. A computer program modeling the process of subtraction wasdevel...
Olga D. Ermolaeva, Sergey A. Lukyanov, Eugene D. S...
JCB
2007
146views more  JCB 2007»
13 years 7 months ago
MSOAR: A High-Throughput Ortholog Assignment System Based on Genome Rearrangement
The assignment of orthologous genes between a pair of genomes is a fundamental and challenging problem in comparative genomics, since many computational methods for solving variou...
Zheng Fu, Xin Chen, Vladimir Vacic, Peng Nan, Yang...
BMCBI
2006
123views more  BMCBI 2006»
13 years 7 months ago
SBEAMS-Microarray: database software supporting genomic expression analyses for systems biology
Background: The biological information in genomic expression data can be understood, and computationally extracted, in the context of systems of interacting molecules. The automat...
Bruz Marzolf, Eric W. Deutsch, Patrick Moss, David...