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BMCBI
2005
73views more  BMCBI 2005»
13 years 8 months ago
Empirical codon substitution matrix
Background: Codon substitution probabilities are used in many types of molecular evolution studies such as determining Ka/Ks ratios, creating ancestral DNA sequences or aligning c...
Adrian Schneider, Gina Cannarozzi, Gaston H. Gonne...
NAR
2011
221views Computer Vision» more  NAR 2011»
12 years 11 months ago
AGRIS: the Arabidopsis Gene Regulatory Information Server, an update
The Arabidopsis Gene Regulatory Information Server (AGRIS; http://arabidopsis.med.ohio-state .edu/) provides a comprehensive resource for gene regulatory studies in the model plan...
Alper Yilmaz, Maria Katherine Mejia-Guerra, Kyle K...
RECOMB
2001
Springer
14 years 9 months ago
Applications of generalized pair hidden Markov models to alignment and gene finding problems
Hidden Markov models (HMMs) have been successfully applied to a variety of problems in molecular biology, ranging from alignment problems to gene nding and annotation. Alignment p...
Lior Pachter, Marina Alexandersson, Simon Cawley
BMCBI
2006
92views more  BMCBI 2006»
13 years 8 months ago
Systematic assignment of thermodynamic constraints in metabolic network models
Background: The availability of genome sequences for many organisms enabled the reconstruction of several genome-scale metabolic network models. Currently, significant efforts are...
Anne Kümmel, Sven Panke, Matthias Heinemann
IJDMB
2010
61views more  IJDMB 2010»
13 years 7 months ago
On a novel coalescent model for genome-wide evolution of Copy Number Variations
: Since we are limited in our knowledge of human demographic history and variations of recombination and mutation rates, large-scale computer simulation is a necessary tool in gene...
Antonina Mitrofanova, Bhubaneswar (Bud) Mishra