Background: Codon substitution probabilities are used in many types of molecular evolution studies such as determining Ka/Ks ratios, creating ancestral DNA sequences or aligning c...
Adrian Schneider, Gina Cannarozzi, Gaston H. Gonne...
The Arabidopsis Gene Regulatory Information Server (AGRIS; http://arabidopsis.med.ohio-state .edu/) provides a comprehensive resource for gene regulatory studies in the model plan...
Alper Yilmaz, Maria Katherine Mejia-Guerra, Kyle K...
Hidden Markov models (HMMs) have been successfully applied to a variety of problems in molecular biology, ranging from alignment problems to gene nding and annotation. Alignment p...
Background: The availability of genome sequences for many organisms enabled the reconstruction of several genome-scale metabolic network models. Currently, significant efforts are...
: Since we are limited in our knowledge of human demographic history and variations of recombination and mutation rates, large-scale computer simulation is a necessary tool in gene...